Strictly indicated for: 🫁 Non-Small Cell Lung Cancer (NSCLC): Specifically for Non-Squamous histology (e.g., Adenocarcinoma). ⚠️ NOT indicated for squamous cell carcinoma. 🏗️ Malignant Pleural Mesothelioma: Cancer of the lung lining, usually treated in combination with Cisplatin.

Dosage and administration

Form: Lyophilized powder for IV infusion (500 mg). ⚠️ MANDATORY PREMEDICATION REGIMEN: To reduce severe toxicity, patients must follow this schedule: 💊 Folic Acid: Start taking daily 7 days prior to the first dose and continue throughout treatment. 💉 Vitamin B12: One injection every 9 weeks (start 1 week before first dose). 💊 Corticosteroids (Dexamethasone): Take the day before, the day of, and the day after infusion to prevent severe skin rash.

Squamous cell carcinoma histology. Pregnancy and breastfeeding. Severe renal impairment (Creatinine clearance < 45 ml/min). Concomitant yellow fever vaccine.

Common side effects (mitigated by vitamins): 📉 Bone Marrow Suppression: Fatigue, anemia, neutropenia (low white blood cells). 🤢 Gastrointestinal: Nausea, vomiting, stomatitis/mucositis. 🔴 Skin: Rash or desquamation (if corticosteroids are skipped).

Pemnat — Pemetrexed 500 mg, 1 pcs, Natco

100% original product

Active ingredient

Pemetrexed

Manufacturer

Natco

Dosage 500 mg

Dosage form Vial

Vials per pack 1

Pemnat (Pemetrexed) 500 mg

Name: Pemnat
Brand: Natco
SKU: PROD-95
Price: 8350 UAH
Availability: InStock

8350₴ ~~9229₴~~ -10%

Pemnat (Pemetrexed 500 mg) is an antifolate chemotherapy agent used for specific types of lung and lining cancers.

Manufacturer: Natco Pharma (India). A generic equivalent of Alimta.

Mechanism of Action:

Pemetrexed disrupts folate-dependent metabolic processes essential for cell replication. By blocking these pathways, it inhibits the DNA and RNA synthesis in cancer cells, causing them to die.

✅ Key Benefit: Considered the standard of care for Malignant Pleural Mesothelioma and Non-Squamous NSCLC.

Strictly indicated for:

🫁 Non-Small Cell Lung Cancer (NSCLC): Specifically for Non-Squamous histology (e.g., Adenocarcinoma). ⚠️ NOT indicated for squamous cell carcinoma.
🏗️ Malignant Pleural Mesothelioma: Cancer of the lung lining, usually treated in combination with Cisplatin.

Form: Lyophilized powder for IV infusion (500 mg).

⚠️ MANDATORY PREMEDICATION REGIMEN:

To reduce severe toxicity, patients must follow this schedule:

💊 Folic Acid: Start taking daily 7 days prior to the first dose and continue throughout treatment.
💉 Vitamin B12: One injection every 9 weeks (start 1 week before first dose).
💊 Corticosteroids (Dexamethasone): Take the day before, the day of, and the day after infusion to prevent severe skin rash.

Squamous cell carcinoma histology.
Pregnancy and breastfeeding.
Severe renal impairment (Creatinine clearance < 45 ml/min).
Concomitant yellow fever vaccine.

Common side effects (mitigated by vitamins):

📉 Bone Marrow Suppression: Fatigue, anemia, neutropenia (low white blood cells).
🤢 Gastrointestinal: Nausea, vomiting, stomatitis/mucositis.
🔴 Skin: Rash or desquamation (if corticosteroids are skipped).

Notice. The information on this page is for reference only and does not replace medical consultation. Always consult a healthcare professional and read the manufacturer's instructions before using any medicine. Self-medication may be dangerous. Information updated: 04.03.2026

Active ingredient

Pemetrexed

Manufacturer

Natco

Dosage 500 mg

Dosage form Vial

Vials per pack 1

100% original product

Delivery across Ukraine

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