Sotoxen 120 — Sotorasib 120 mg Tablets

Indicated specifically for:

• 🎗️ Non-Small Cell Lung Cancer (NSCLC): Locally advanced or metastatic.
• 🧬 Genetic Requirement: Presence of KRAS G12C mutation is mandatory. A valid FDA-approved test is required before starting treatment.
• For adult patients who have received at least one prior systemic therapy.

Packaging: Bottle of 56 Tablets (120 mg each).

⚠️ ADMINISTRATION PROTOCOL:

• 💊 Standard Dosage: 960 mg orally once daily (Total 8 tablets of 120 mg). Dose reduction may be required based on toxicity.
• 🕒 Timing: Take at the same time every day.
• 🍽️ Food: Can be taken with or without food. Swallow tablets whole; do not chew, crush, or split.
• Do not take a missed dose if more than 6 hours have passed.

• History of Interstitial Lung Disease (ILD) or Pneumonitis.
• Severe hepatic impairment.
• Pregnancy and breastfeeding (embryo-fetal toxicity).

Common side effects to monitor:

• 🚽 Gastrointestinal: Diarrhea (most common), nausea.
• 🦴 Musculoskeletal: Arthralgia (joint pain) or muscle pain.
• ⚠️ Hepatotoxicity: Elevated liver enzymes (ALT/AST). Regular liver function tests (LFTs) are crucial.
• New or worsening cough/shortness of breath (sign of ILD).