Upajak — Upadacitinib 15 mg Tablets

Prescribed by rheumatologists, dermatologists, or gastroenterologists for:

• 🔹 Rheumatoid Arthritis (RA): Moderate to severe active RA in patients who have had an inadequate response to DMARDs (e.g., methotrexate).
• 🔹 Psoriatic Arthritis (PsA): To reduce joint pain, swelling, and stiffness.
• 🔹 Ankylosing Spondylitis (AS).
• 🔹 Atopic Dermatitis: For refractory moderate to severe eczema.
• 🔹 Ulcerative Colitis & Crohn's Disease.

Sales Unit: 1 Bottle (30 Tablets of 15 mg).

⚠️ ADMINISTRATION GUIDELINES:

• Standard Dosage: 15 mg (1 tablet) once daily. Should be taken at approximately the same time each day.
• How to take: Swallow the tablet whole with water. Can be taken with or without food.
• ⛔ IMPORTANT: Do NOT chew, crush, or break the tablet, as this affects the extended-release mechanism.
• Missed Dose: Take as soon as remembered unless it is almost time for the next dose. Do not double the dose.

• ⛔ Active Serious Infections: Active tuberculosis (TB), sepsis, or opportunistic infections must be ruled out before starting.
• Severe hepatic impairment.
• Pregnancy and breastfeeding (potential risk to the fetus).
• Children under 12 years or body weight less than 40 kg.
• Hypersensitivity to Upadacitinib.

Regular medical monitoring is advised. Potential side effects:

• 🦠 Infections: Upper respiratory tract infections (common cold, sore throat).
• 📉 Skin: Acne, potential reactivation of herpes zoster (shingles).
• 🩸 Labs: Elevations in lipids (cholesterol), liver enzymes, or decrease in neutrophils.
• ⚠️ Rare but Serious: Increased risk of thrombosis (blood clots) in high-risk patients.