Approved for the treatment of adult patients with: Chronic Lymphocytic Leukemia (CLL): Treatment-naive or relapsed/refractory. Small Lymphocytic Lymphoma (SLL). Mantle Cell Lymphoma (MCL): Second-line therapy.

Dosage and administration

Dosage: 100 mg capsule taken twice daily (BID). ⚠️ CRITICAL ABSORPTION WARNING (Acid Dependency): This drug needs stomach acid to work. 🚫 Do NOT take PPIs: Avoid Omeprazole, Esomeprazole, Lansoprazole. They reduce drug concentration significantly. ✅ Antacids: Take Acalnib at least 2 hours before taking calcium carbonate or other antacids. ✅ H2-blockers: Take Acalnib 2 hours before Famotidine/Ranitidine.

Severe bleeding disorders. Upcoming surgery (Stop drug 3-7 days prior). Severe hepatic impairment. Pregnancy and breastfeeding. Concomitant use of Warfarin (increases bleeding risk).

Side effects are generally mild: Headache: A known "Acalabrutinib headache" often occurs early in treatment but usually resolves. Caffeine helps. Bruising: Minor subcutaneous bleeding (petechiae). Infections: Neutropenia (low white blood cell count). Diarrhea.

Acalnib — Acalabrutinib 100 mg, 30 pcs, Hetero

100% original product

Active ingredient

Acalabrutinib

Manufacturer

Hetero

Dosage 100 mg

Dosage form Capsules

Capsules per pack 30

Acalnib (Acalabrutinib) 100 mg

Name: Acalnib
Brand: Hetero
SKU: PROD-72
Price: 9229 UAH
Availability: InStock

9229₴ ~~10108₴~~ -9%

Acalnib 100 mg is a next-generation targeted cancer therapy. Active ingredient: Acalabrutinib (100 mg).

Manufacturer: Hetero Healthcare (India). A generic version of the breakthrough drug Calquence.

Why switch to Acalabrutinib?

Unlike Ibrutinib, Acalnib is a highly selective BTK inhibitor. It binds specifically to the target without interfering with other kinases (like EGFR). This results in a much lower incidence of atrial fibrillation (heart rhythm issues) and bleeding events.

✅ Patient Profile: Ideal for patients who cannot tolerate Ibrutinib due to cardiovascular toxicity.

Approved for the treatment of adult patients with:

Chronic Lymphocytic Leukemia (CLL): Treatment-naive or relapsed/refractory.
Small Lymphocytic Lymphoma (SLL).
Mantle Cell Lymphoma (MCL): Second-line therapy.

Dosage: 100 mg capsule taken twice daily (BID).

⚠️ CRITICAL ABSORPTION WARNING (Acid Dependency):

This drug needs stomach acid to work.

🚫 Do NOT take PPIs: Avoid Omeprazole, Esomeprazole, Lansoprazole. They reduce drug concentration significantly.
✅ Antacids: Take Acalnib at least 2 hours before taking calcium carbonate or other antacids.
✅ H2-blockers: Take Acalnib 2 hours before Famotidine/Ranitidine.

Severe bleeding disorders.
Upcoming surgery (Stop drug 3-7 days prior).
Severe hepatic impairment.
Pregnancy and breastfeeding.
Concomitant use of Warfarin (increases bleeding risk).

Side effects are generally mild:

Headache: A known "Acalabrutinib headache" often occurs early in treatment but usually resolves. Caffeine helps.
Bruising: Minor subcutaneous bleeding (petechiae).
Infections: Neutropenia (low white blood cell count).
Diarrhea.

Notice. The information on this page is for reference only and does not replace medical consultation. Always consult a healthcare professional and read the manufacturer's instructions before using any medicine. Self-medication may be dangerous. Information updated: 02.03.2026

Active ingredient

Acalabrutinib

Manufacturer

Hetero

Dosage 100 mg

Dosage form Capsules

Capsules per pack 30

100% original product

Delivery across Ukraine

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