Capixet Tablets — Capecitabine 500 mg (14 Tabs) Everest

Prescribed by oncologists for the treatment of adult patients with:

• 🔹 Colorectal Cancer: Adjuvant treatment of stage III colon cancer and metastatic colorectal cancer.
• 🔹 Gastric Cancer: First-line treatment for advanced gastric cancer.
• 🔹 Breast Cancer: Metastatic or locally advanced breast cancer (as monotherapy or combined with docetaxel) after failure of anthracycline-containing chemotherapy.

Sales Unit: Bottle containing 14 film-coated tablets (500 mg strength).

⚠️ APPLICATION INSTRUCTIONS:

• Dosage Calculation: Strictly prescribed by a doctor based on body surface area (BSA).
• Regimen: Typically taken twice daily (morning and evening) for 14 days, followed by a 7-day rest period.
• Administration: Swallow tablets whole with water within 30 minutes after a meal. Do not crush or chew (hazardous drug!).
• ✋ Missed Dose: Do not take the missed dose at a later time and do not double the next dose. Continue with the regular schedule.

• ⛔ DPD Deficiency: Known complete absence of dihydropyrimidine dehydrogenase activity (risk of life-threatening toxicity).
• Pregnancy and Breastfeeding.
• Severe renal or hepatic impairment.
• Severe leukopenia, neutropenia, or thrombocytopenia.

Potential side effects may occur requiring monitoring:

• ⚠️ Hand-Foot Syndrome: Redness, swelling, peeling, numbness, or pain on the palms of hands and soles of feet (characteristic of capecitabine).
• 🤢 Gastrointestinal: Diarrhea (requires immediate management), nausea, vomiting, stomatitis (mouth sores), abdominal pain.
• 😴 General: Fatigue, asthenia (weakness).
• 🩸 Hematologic: Decreased white blood cell or platelet counts (risk of infection/bleeding).