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Hetenza 40 mg (Enzalutamide) is a potent next-generation anti-androgen medication designed for the treatment of prostate cancer. The drug acts as a selective inhibitor of the androgen receptor signaling pathway. Unlike first-generation anti-androgens, Hetenza blocks several stages of male sex hormone signaling that stimulate tumor cell growth.
Manufacturer: Heet Health Care. Hetenza is a high-quality generic medication containing the same active ingredient as the original drug, ensuring the availability of effective therapy while maintaining international quality standards.
Key Features:
- ✅ Triple Action: Inhibits androgen binding to receptors, blocks receptor translocation into the cell nucleus, and prevents its binding to DNA.
- ✅ High Efficacy: Proven to increase overall survival and delay disease progression in patients with metastatic cancer.
- ✅ Convenience: The oral capsule form allows for treatment in a home setting.
Hetenza is prescribed by an oncologist or urologist for the treatment of men with the following diagnoses:
- 🔹 Metastatic castration-resistant prostate cancer (mCRPC).
- 🔹 Non-metastatic castration-resistant prostate cancer with a high risk of developing metastases.
- 🔹 Metastatic hormone-sensitive prostate cancer (mHSPC) in combination with androgen deprivation therapy.
Sales Form: 1 pack contains 4 blisters of 28 capsules (112 capsules of 40 mg in total).
⚠️ INSTRUCTIONS FOR USE:
- Dosage Regimen: The recommended daily dose is 160 mg (4 capsules of 40 mg) once daily.
- Method of Administration: Capsules should be swallowed whole, without chewing or opening. Take at the same time each day, regardless of food intake.
- Important: Do not stop treatment without consulting your doctor. Treatment usually continues until disease progression or unacceptable toxicity occurs.
- Storage: Store in a dry place, protected from light, at temperatures up to 25°C.
- ⛔ Partner Pregnancy: The drug is not intended for women, but men must use reliable contraception (including condoms) as enzalutamide may harm the fetus.
- ⛔ Seizure Activity: Use with caution in patients with a predisposition to seizures or a history of epilepsy.
- Hypersensitivity to enzalutamide or other components of the drug.
- Severe renal or hepatic impairment (requires strict medical supervision).
Therapy may cause side effects requiring medical observation:
- 🏃♂️ General: Increased fatigue, severe weakness (asthenia).
- 🔥 Vascular: Hot flashes, increased blood pressure (hypertension).
- 🦴 Musculoskeletal: Bone and joint pain, increased risk of fractures.
- 🧠 Neurological: Headache, in rare cases — risk of seizures.
- 🤢 Gastrointestinal: Decreased appetite, nausea, diarrhea.
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