Honvan — Fosfestrol 120 mg

Indicated for the treatment of:

• Advanced Prostate Cancer: Particularly metastatic carcinoma of the prostate.
• Hormone-Refractory Cases: Used when the tumor stops responding to standard androgen deprivation therapy.
• Relief of bone pain associated with metastases.

Tablets 120 mg. Dosage is strictly individualized by the oncologist.

Initial Phase:

• Typically high doses: 2 tablets 3 times daily (360-720 mg/day) for the first week.
• Followed by a gradual reduction.

Maintenance Dose: Usually 1-2 tablets (120-240 mg) daily.

💊 Take orally with water. Taking after meals may reduce nausea.

• Thromboembolic Disorders: History of blood clots, thrombophlebitis, or stroke (Estrogens increase clotting risk).
• Severe liver dysfunction.
• Severe cardiovascular disease or heart failure.

Side effects are typical of estrogen therapy:

• Feminization: Gynecomastia (swelling/tenderness of breasts), decreased libido.
• Fluid Retention: Edema (swelling of feet and ankles).
• Gastrointestinal: Nausea, vomiting.
• Cardiovascular: Increased risk of thrombosis and elevated blood pressure.