Talaparib — Talazoparib 1 mg Capsules

Prescribed by oncologists typically after confirmation via a genetic test:

• 🔹 Breast Cancer: Treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) HER2-negative locally advanced or metastatic breast cancer.

Sales Unit: 1 Bottle (30 Capsules of 1 mg).

⚠️ ADMINISTRATION GUIDELINES:

• Standard Dosage: 1 mg (1 capsule) taken once daily. Ideally taken at the same time each day.
• How to take: Swallow the capsule whole with water. Can be taken with or without food.
• ⛔ Important: Do not open, crush, dissolve, or chew the capsules.
• Missed Dose or Vomiting: If you vomit or miss a dose, do NOT take an extra dose. Resume the regular schedule the next day.

• ⛔ Pregnancy and Breastfeeding: Can cause fetal harm. Effective contraception is mandatory during treatment and for 7 months after.
• Moderate to severe renal impairment (requires dose adjustment).
• Children (under 18 years of age).
• Hypersensitivity to Talazoparib.

Monthly blood tests are required to monitor for bone marrow suppression. Potential side effects:

• 🩸 Hematologic (Very Common): Anemia (low red blood cells), neutropenia (low white blood cells), thrombocytopenia (low platelets). Blood transfusions may be necessary.
• 📉 General: Fatigue, weakness (asthenia).
• 🤢 Gastrointestinal: Nausea, vomiting, decreased appetite.
• 💇‍♀️ Skin: Alopecia (hair loss).