Zoldonat — Zoledronic Acid 4 mg, 1 pcs, Natco
100% original product

Zoldonat (Zoledronic Acid) 4 mg — 1 Vial

1187₴ 1318₴ -10%

Zoldonat is a potent bisphosphonate injection used in oncology care. Active ingredient: Zoledronic Acid (4 mg).

Manufacturer: Natco Pharma (India). Generic equivalent of Zometa.

Mechanism of Action:

It inhibits osteoclast activity, effectively stopping the breakdown of bone tissue. In cancer patients with bone metastases, Zoldonat strengthens the bones, reduces pain, and prevents serious skeletal complications like fractures.

✅ Key Benefit: Reduces the risk of Skeletal Related Events (SREs) in patients with advanced malignancies involving bone.

Indicated for:

  • Bone Metastases: From solid tumors (breast cancer, prostate cancer, lung cancer, etc.) and Multiple Myeloma.
  • Hypercalcemia of Malignancy (HCM): Life-threatening high calcium levels induced by cancer.

Form: Lyophilized powder (must be reconstituted and diluted).

Administration:

  • 💉 Intravenous infusion over no less than 15 minutes. Administered every 3-4 weeks.
  • Patient must be well-hydrated prior to infusion.

⚠️ CRITICAL WARNINGS:

  • Dental Health: Complete all invasive dental work BEFORE starting therapy. Risk of Osteonecrosis of the Jaw (ONJ).
  • Supplements: Patients usually take oral Calcium (500 mg) and Vitamin D (400 IU) daily, unless treating hypercalcemia.
  • Severe renal impairment (Creatinine clearance < 30 mL/min).
  • Pregnancy and breastfeeding.
  • Hypocalcemia (low calcium levels).

"Post-Dose Syndrome":

Fever, chills, bone pain, and muscle aches are very common within the first 3 days of administration. This is temporary and can be managed with Paracetamol/Ibuprofen.

Serious Risks:

  • Renal toxicity (Serum creatinine monitoring is mandatory before each dose).
  • Osteonecrosis of the Jaw (ONJ).

Notice. The information on this page is for reference only and does not replace medical consultation. Always consult a healthcare professional and read the manufacturer's instructions before using any medicine. Self-medication may be dangerous. Information updated: 13.03.2026

Active ingredient
Zoledronic Acid
Manufacturer
Natco
Dosage 4 mg
Dosage form Vial
Vials per pack 1
100% original product
Delivery across Ukraine
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