Tofajak (Tofacitinib) 5 mg

Indicated for adult patients with moderate to severe:

• 🦴 Rheumatoid Arthritis (RA): For patients who have had an inadequate response to Methotrexate.
• 🖐️ Psoriatic Arthritis (PsA).
• 🚽 Ulcerative Colitis (UC).
• Ankylosing Spondylitis.

Packaging: Bottle of 60 Tablets (5 mg each).

⚠️ ADMINISTRATION PROTOCOL:

• 💊 Standard Dosage: 5 mg taken orally twice daily (BID).
• 🍽️ Food: May be taken with or without food. Swallow whole.
• Adjustment: Dosage may be reduced to once daily in patients with moderate renal/hepatic impairment or those taking strong CYP3A4 inhibitors.

• Active serious infections (including localized infections). Screening for Tuberculosis (TB) is mandatory prior to administration.
• Severe hepatic impairment.
• Pregnancy and breastfeeding.
• History of thrombosis (blood clots).

Potential side effects to monitor:

• 🦠 Infections: Upper respiratory tract infections (common cold), nasopharyngitis.
• 🔥 Herpes Zoster: Increased risk of shingles.
• 🩸 Thrombosis: Use with caution due to risk of pulmonary embolism (PE) and deep vein thrombosis (DVT).
• Increased cholesterol levels.