Caboxen 80 (Cabozantinib) 80 mg Capsules
25943₴
27702₴
-6%
Caboxen 80 mg (Cabozantinib) is a high-strength tyrosine kinase inhibitor targeting VEGFR, MET, and AXL pathways used in advanced oncology.
Manufacturer: Everest Pharmaceuticals. Each pack contains 30 capsules. This 80 mg strength is primarily utilized in treatment regimens requiring higher daily dosages, such as for medullary thyroid cancer, effectively cutting off the tumor's blood supply.
Key Feature:
Designed to overcome tumor resistance. The 80 mg capsule is a key component of the 140 mg daily protocol (often combined with 20 mg capsules) for specific thyroid cancers.
Indicated for adult patients with:
- 🔹 Progressive Medullary Thyroid Cancer (MTC): Typically used as part of the starting dose regimen (140 mg daily).
- 🔹 Advanced Renal Cell Carcinoma (RCC) / Hepatocellular Carcinoma (HCC): Depending on oncologist prescription and dose modifications.
Packaging: 80 mg capsules.
⚠️ ADMINISTRATION PROTOCOL:
- Dosage: As prescribed. Often taken once daily.
- Food Intake: ⛔ Must be taken on an empty stomach. No food for at least 2 hours before and 1 hour after administration.
- Administration: Swallow whole with a full glass of water. Do not open or crush.
- Warning: Avoid grapefruit products as they increase blood levels of the drug.
- Hypersensitivity to Cabozantinib.
- Recent history of severe hemorrhage or GI perforation.
- Severe hepatic impairment.
- Pregnancy and breastfeeding.
Common adverse reactions include:
- 🩸 Cardiovascular: Hypertension, venous thromboembolism.
- 📉 Gastrointestinal: Diarrhea (frequent), nausea, mucositis, abdominal pain.
- 🖐 Dermatologic: Hand-foot skin reaction (PPES), hair color changes.
- 🌀 Systemic: Fatigue, weight loss, decreased appetite.
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