Crikzo — Crizotinib 250 mg, 30 pcs, Hetero
100% original product

Crikzo (Crizotinib) 250 mg

19118 21052 -9%

Crikzo (Crizotinib 250 mg) is an oral targeted therapy known as a Tyrosine Kinase Inhibitor (TKI).

Manufacturer: Hetero Healthcare (India). It is a generic version of Xalkori. Instead of killing all rapidly dividing cells like chemotherapy, Crikzo specifically targets cancer cells that harbor specific genetic mutations.

Mechanism of Action ("Signal Blocker"):

Crizotinib works by inhibiting the ALK (Anaplastic Lymphoma Kinase) or ROS1 proteins. In patients with these specific gene mutations, the protein acts like a stuck gas pedal, driving cancer growth. Crikzo blocks this protein, effectively taking the foot off the gas pedal, causing the tumor to stop growing or shrink.

Key Benefit: Significant improvement in progression-free survival for patients with specific genetic biomarkers.

Indicated for the treatment of:

  • 🫁 Non-Small Cell Lung Cancer (NSCLC): Advanced or metastatic stage.
  • 🧬 Requirement: Tumors must be confirmed as ALK-positive or ROS1-positive via an FDA-approved test.
  • It is not effective for patients without these specific mutations.

Packaging: 30 Capsules (250 mg each).

⚠️ DOSAGE & ADMINISTRATION:

  • 💊 Standard Dose: 250 mg taken orally twice daily (BID).
  • 🍽 Intake: Swallow capsules whole. Can be taken with or without food. Do not crush or chew.
  • Grapefruit and grapefruit juice should be avoided during treatment as they increase drug levels in the blood.
  • Pregnancy (can cause fetal harm) and breastfeeding.
  • Congenital Long QT Syndrome.
  • Severe renal or hepatic impairment.
  • Hypersensitivity to Crizotinib.

Common side effects to be aware of:

  • 👀 Visual Disturbances: Trails of light, flashes, or blurred vision (very common, usually mild).
  • 🤢 Gastrointestinal: Nausea, diarrhea, vomiting, constipation.
  • ❤️ Cardiac: Bradycardia (slow heart rate), QT prolongation.
  • Edema (swelling) and elevated liver enzymes.

Notice. The information on this page is for reference only and does not replace medical consultation. Always consult a healthcare professional and read the manufacturer's instructions before using any medicine. Self-medication may be dangerous. Information updated: 07.03.2026

Active ingredient
Manufacturer
Hetero
Dosage 250 mg
Dosage form Capsules
Capsules per pack 30
100% original product
Delivery across Ukraine
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