Reditux 100 (Rituximab) 100 mg

Indicated for treatment of:

• 🎗️ Non-Hodgkin’s Lymphoma (NHL): Follicular lymphoma and Diffuse Large B-Cell Lymphoma (DLBCL).
• 🩸 Chronic Lymphocytic Leukemia (CLL).
• 🦴 Rheumatoid Arthritis: For patients with inadequate response to TNF-inhibitors.
• Granulomatosis with Polyangiitis (Wegener’s).

Dosage Form: 10 ml Vial (Concentration 10 mg/ml).

⚠️ ADMINISTRATION PROTOCOL:

• IV Infusion Only: Must be administered as a slow intravenous infusion. NEVER as a push or bolus.
• 💊 Premedication: Pre-treatment with an analgesic (acetaminophen) and an antihistamine (diphenhydramine) is mandatory to reduce infusion reactions. Glucocorticoids are also often used.

🚑 First Infusion Warning: The infusion rate starts very slowly. Most side effects occur during the first administration.

• ☢️ Active Hepatitis B Infection: Screening for Hepatitis B virus (HBV) is mandatory before starting treatment. Reactivation can be fatal.
• Severe, active infections (e.g., tuberculosis, sepsis).
• Severe heart failure (NYHA Class IV).

Common side effects to monitor:

• 🌡️ Infusion-related reactions: Fever, chills, and rigors are very common during the first infusion.
• 📉 Lymphopenia/Neutropenia: Low white blood cell counts, increasing susceptibility to infections.
• Hypotension (Low blood pressure).