Sutinat Capsules — Sunitinib 50 mg (28 Capsules) Natco
Sutinat 50 mg (Sunitinib) is a multi-targeted antitumor drug belonging to the class of tyrosine kinase inhibitors. It possesses the unique ability to block multiple receptors involved in tumor growth, pathological angiogenesis (the formation of new blood vessels that feed the tumor), and cancer metastasis. Sutinat acts on VEGFR, PDGFR, KIT, and RET receptors, providing a powerful therapeutic effect for various types of solid tumors.
Manufacturer: NATCO Pharma Ltd. Sutinat is a high-quality generic of the original drug Sutent. NATCO's production is certified according to international standards, which guarantees patients a high degree of active substance purification and stable efficacy at a significantly more affordable cost.
Key Features:
- ✅ Multi-targeted Action: Simultaneously inhibits key tumor cell survival pathways, making it difficult for resistance to develop.
- ✅ Anti-angiogenic Effect: "Starves" the tumor by blocking the growth of blood vessels that supply it.
- ✅ Golden Standard: Included in international treatment protocols for metastatic renal cancer as one of the most effective first-line drugs.
Sutinat is prescribed by an oncologist for the treatment of adult patients with the following conditions:
- 🔹 Metastatic Renal Cell Carcinoma (mRCC): As first-line therapy or when previous cytokine therapy has been ineffective.
- 🔹 Gastrointestinal Stromal Tumors (GIST): In the absence of a response to imatinib therapy or its intolerance.
- 🔹 Pancreatic Neuroendocrine Tumors (pNET): Progressive, well-differentiated tumors in patients with unresectable or metastatic disease.
Sales Form: 1 pack contains 28 capsules of 50 mg sunitinib.
⚠️ INSTRUCTIONS FOR USE:
- Dosage Regimen: For renal cancer and GIST, the standard dose is 50 mg (1 capsule) per day. Treatment is carried out in cycles: 4 weeks of intake, followed by a 2-week break (4/2 schedule).
- Method of Administration: Capsules are taken orally, swallowed whole with water. Intake is possible regardless of food.
- Dose Correction: Depending on individual tolerance and side effects, the doctor may change the dosage to 37.5 mg or 25 mg.
- Storage: In the original packaging at a temperature not exceeding 25°C, out of reach of children.
- ⛔ Pregnancy and Lactation: The drug has embryotoxic effects. Categorically contraindicated. Women of reproductive age must use reliable contraception.
- ⛔ Cardiovascular Pathologies: Use with caution in case of uncontrolled arterial hypertension and QT interval prolongation.
- ⛔ Hepatic and Renal Impairment: Strict medical monitoring of organ function is required.
- Pediatric use (efficacy and safety for children have not been established).
- Hypersensitivity to sunitinib.
Sunitinib treatment should be conducted under the regular supervision of an oncologist. Possible side effects:
- 🧪 Hematology: Decreased levels of white blood cells, platelets, and hemoglobin.
- 🏃♂️ General: Increased fatigue, asthenia, changes in skin color (yellowing) and hair.
- 🤢 GI Tract: Stomatitis (mouth sores), diarrhea, change in taste sensations, nausea.
- 🩺 Endocrine System: Hypothyroidism (regular monitoring of TSH levels is required).
- 🩸 Cardiology: Increased blood pressure, decreased left ventricular ejection fraction.
- 💅 Skin: Palmar-plantar erythrodysesthesia syndrome (redness, swelling, and tingling in the palms and soles).
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