Nexataf (Tenofovir Alafenamide) Tablets
Nexataf 25 mg (Tenofovir Alafenamide) is a potent nucleotide reverse transcriptase inhibitor (NRTI) indicated for the treatment of chronic hepatitis B virus (HBV) infection.
Manufacturer: Everest Pharmaceuticals. Each pack contains 30 film-coated tablets.
Mechanism of Action:
Nexataf is a "prodrug" of tenofovir that targets hepatocytes (liver cells). It demonstrates high antiviral efficacy at a dose 10 times lower than the older generation (TDF). This targeted delivery results in roughly 90% less active drug in the bloodstream, significantly reducing the risk of kidney toxicity and bone density loss.
✅ Benefit: Powerful viral suppression with an improved safety profile for long-term use.
Indicated for the treatment of chronic Hepatitis B in adults and adolescents (aged 12+ with body weight ≥ 35 kg):
- 🦠 Chronic Hepatitis B: For patients with compensated liver disease.
- 🛡️ High-Risk Patients: Preferred option for patients with history of renal impairment or bone disease (osteoporosis).
Packaging: 25 mg tablets.
⚠️ ADMINISTRATION PROTOCOL:
- 💊 Dose: One tablet (25 mg) taken orally once daily.
- 🍲 With Food: Must be taken with food to ensure proper absorption.
- 🕒 Consistency: Take at the same time each day.
- 🚫 Missed Dose: If missed by less than 18 hours, take immediately with food. If more than 18 hours, skip and take the next scheduled dose. Do not double up.
- Hypersensitivity to Tenofovir Alafenamide.
- Children under 12 years of age or weighing less than 35 kg.
- Breastfeeding.
- Warning: Patients co-infected with HIV should not use this drug alone, as it may lead to HIV resistance.
Most common adverse reactions include:
- 🤯 Neurological: Headache, dizziness.
- 🤢 Gastrointestinal: Nausea, abdominal pain, diarrhea, flatulence.
- 💤 General: Fatigue.
- ⚠️ Severe Exacerbation: Discontinuation of therapy may result in severe acute exacerbations of Hepatitis B. Liver function should be monitored closely after stopping treatment.
What Customers Say
No reviews yet
Your review can be the first!