Naivex Tablets — Dolutegravir 50 mg (30 Tablets) Hetero
Naivex 50 mg (Dolutegravir) is a potent next-generation antiretroviral drug designed for the treatment of HIV-1 infection. It belongs to the class of integrase strand transfer inhibitors (INSTIs) and blocks the enzyme that the virus uses to integrate its genetic material into human cells. Naivex is recognized as one of the most effective components of antiretroviral therapy due to its rapid suppression of viral load and high genetic barrier to the development of viral resistance.
Manufacturer: Hetero Healthcare. Naivex is a high-quality generic of the original drug Tivicay. The medication is produced at facilities certified according to international standards (WHO GMP), which guarantees full bioequivalence to the original and a high degree of active substance purification.
Key Features:
- ✅ High Efficacy: Rapidly reduces the number of virus copies in the blood to an undetectable level.
- ✅ Protection against Resistance: It is extremely difficult for the virus to develop resistance to dolutegravir compared to previous generation drugs.
- ✅ Convenience: The small tablet size and once-daily dosing significantly simplify adherence to the treatment regimen.
Naivex is prescribed by an infectious disease specialist for the treatment of adults and adolescents (weighing more than 40 kg) with the following indications:
- 🔹 Treatment of HIV-1 infection as part of combination antiretroviral therapy (ART).
- 🔹 Can be used in treatment-naive patients (those who have not previously received treatment) as well as treatment-experienced patients (in the absence of resistance to integrase inhibitors).
Sales Form: 1 bottle containing 30 tablets of 50 mg dolutegravir.
⚠️ INSTRUCTIONS FOR USE:
- Dosage Regimen: The standard dose for most patients is 50 mg (1 tablet) once daily. If resistance to other integrase inhibitors is present, the doctor may prescribe twice-daily dosing.
- Method of Administration: Tablets are taken orally, regardless of food intake. It is advisable to take the drug at the same time each day.
- Interaction with Antacids: If you take medications for heartburn containing aluminum, magnesium, or calcium, take Naivex 2 hours before or 6 hours after them.
- Storage: Store at temperatures up to 30°C in a dry place, in a tightly closed bottle.
- ⛔ Drug Interaction: Co-administration with dofetilide (heart medication) and pimozide is strictly prohibited.
- ⛔ Weight: Not intended for children and adolescents weighing less than 40 kg.
- ⛔ Pregnancy: The decision to take the drug is made strictly by the treating physician. It is recommended to use reliable methods of contraception during therapy.
- Hypersensitivity to dolutegravir or any component of the drug.
Naivex is usually very well tolerated; side effects occur rarely and often resolve on their own within the first weeks of intake:
- 🧠 Central Nervous System: Insomnia, headache, unusual dreams, dizziness.
- 🤢 GI Tract: Nausea, diarrhea, slight abdominal discomfort.
- 🏃♂️ General: Fatigue, skin rash (in rare cases, serious allergic reactions are possible).
- 🧪 Laboratory Parameters: A slight increase in blood creatinine levels (usually does not affect kidney function).
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